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International Journal of Mathematics Trends and Technology

Research Article | Open Access | Download PDF

Volume 52 | Number 2 | Year 2017 | Article Id. IJMTT-V52P520 | DOI : https://doi.org/10.14445/22315373/IJMTT-V52P520

Mathematical models of two phase human hepatic blood flow in venules with special reference to liver cirrhosis


Anil Kumar, V. Upadhyay, A. K. Agrawal, P. N. Pandey
Abstract

Present paper visualize a model of two phased blood flow in hepatic venules, keeping in view the nature of hepatic blood circulationin human body. The viscosity increases in the venules due to formation of rouleaux along axis of red bloodcells. We have applied the Herschel Bulkley Non-Newtonian model in Bio- fluid mechanical setup with thehelp of clinical data in case of Liver Cirrhosis for hemoglobin versus blood pressure. The overall presentationis in tensorial form and the solution technique adopted is analytical as well as numerical. The role ofhematocrit is explicit in the determination of blood pressure in case of Hepatic disease Liver Cirrhosis thegraphical presentation for particular parametric value is much close to the clinical observation.

Keywords
Structure of the Liver, Hematocrit, Liver Cirrhosis, Hepatic Blood Flow, Herschel Bulkley Non-Newtonian model etc.
References

1. Zatonski WA, et al. Liver cirrhosis mortality in Europe, with special attention to Central and Eastern Europe. Eur Addict Res. 2010; 16:193-201.
2. Mokdad A, et al. Liver cirrhosis mortality in 187 countries between 1980 and 2010: a systematic analysis. BMC Med. 2014; 12:145.
3. Cirrhosis overview National Digestive Information Clearing house, Retrieved on 01 -22, 2010.
4. Upadhyay, V. 2000. Some phenomena in two phase blood flow. Ph. D. Thesis, Central University, Allahabad.Pp.123.i
5. Upadhyay V., Pandey P. N., Chaturvedi S. K., Upadhyay A. 2012. A Mathematical Model on Effect of Stenosis in Two Phase Blood Flow in Arteries Remote from the Heart, Journal of International Academy of Physical Sciences, Vol. 16 No.3, pp. 247-257.
6. Singh P. and Upadhyay K.S.; a new approach for the shock propagation in the two phase system; NAT. Acad. Sc.; Letters, 1986; 8(2):112-118 .
7. Glenn Elert 2010. “Viscosity, the physics hypertext book”.
8. Ottesen, J.T., M.S. Olufsen, and J.K. Larsen, 2006. Applied Mathematical Models in Human Physiology. (Table 2.3: Physiological data for the various parameters in the circulatory system (Caro et al., 1978).

Citation :

Anil Kumar, V. Upadhyay, A. K. Agrawal, P. N. Pandey, "Mathematical models of two phase human hepatic blood flow in venules with special reference to liver cirrhosis," International Journal of Mathematics Trends and Technology (IJMTT), vol. 52, no. 2, pp. 145-151, 2017. Crossref, https://doi.org/10.14445/22315373/IJMTT-V52P520

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