Volume 70 | Issue 1 | Year 2024 | Article Id. IJMTT-V70I1P105 | DOI : https://doi.org/10.14445/22315373/IJMTT-V70I1P105
Received | Revised | Accepted | Published |
---|---|---|---|
02 Dec 2023 | 05 Jan 2024 | 18 Jan 2024 | 31 Jan 2024 |
Here an HIV/AIDS epidemical model has been taken with awareness and treatment. The disease spreadsin a variable
size population through a horizontal transmission that is by contact. The equilibrium points of the reckon model are found and
their stability is investigated. The basic reproductive numbers of the proposed model have been calculated using the nextgeneration matrix technique, which plays an important role in discussing the model. When the basic reproductive number R0, its
value is less than one disease-free equilibrium E0 is locally asymptotically stable and unstable while R0 > 1. If R0 > 1, then
the endemic equilibrium point 𝐸
∗
is asymptotically stable, which is calculated using the Jacobian matrix. Also, discuss the
effect of treatment and awareness with the help of sensitivity analysis. Finally, find out some sensitive parameters that are more
reliable to decrease disease transmission. The considered model has been solved numerically and the model’s numerical solution
justifies the analytical outcomes.
HIV/AIDS Epidemic, Basic Reproductive Number, Local Stability, Aware- ness, Treatment, and Numerical
Outcomes.
[1] Centers for Disease Control(CDC), “ Pneumocystis Pneumonia - Los Angeles, ” Morbidity and Mortality Weekly Report (MMWR),
vol. 30, pp. 250-252, 1981.
[Google Scholar] [Publisher Link]
[2] Centers for Disease Control(CDC), “Update on Acquired Immune Deficiency Syndrome (AIDS) - United States,” Morbidity and
Mortality Weekly Report (MMWR), vol. 31, pp. 507-514, 1982.
[Google Scholar] [Publisher Link]
[3] John Coffin et al., “Human Immunodeficiency Viruses,” Science, vol. 232, no. 4751, p. 697, 1986.
[CrossRef] [Google Scholar] [Publisher Link]
[4] AnnualReport 2013-14, The Department of AIDS Control, Ministry of Health and Family Welfare, Government of India. [Online].
Available. https://naco.gov.in/sites/default/files/NACO_English%202013-14.pdf
[5] Annual Report 2008-2009, National AIDS Control Organization, NACO, Ministry of Health, Government of India. [Online].
Available. https://naco.gov.in/sites/default/files/Annual_Report_NACO_2008-09.pdf
[6] UNAIDS, HIV Estimates with Uncertainty Bounds, 1990- 2012, Report on the Global AIDS Epidemi 2013. [Online]. Available.
https://www.unaids.org/sites/default/files/media_asset/UNAIDS_Global_Report_2013_en_1.pdf
[7] R.O. Simwa, and G.P. Pokhariyal, “A Dynamical Model for Stage-Specific HIV Incidences with Application to Sub-Saharan
Africa,” Applied Mathematics and Computation, vol. 146, no. 1, pp. 93-104, 2003.
[CrossRef] [Google Scholar] [Publisher Link]
[8] Centers for Disease Control and Prevention, “HIV Transmission through Transfusion-Missouri and Colorado,” Morbidity and
Mortality Weekly Report (MMWR), vol. 15, pp. 1335-1339, 2010.
[Google Scholar] [Publisher Link]
[9] J. Collazos, V. Asensi, and J.A. Carton, “Association of HIV Transmission Categories with Socio Demographic, Viroimmunological
and Clinical Parameters of HIV- Infected Patients, Epidemiology and Infection, vol. 138, no. 7, pp. 1016-1024, 2010.
[CrossRef] [Google Scholar] [Publisher Link]
[10] R.M. Anderson et al., “A Preliminary Study of the Transmission Dynamics of the Human Immunodeficiency Virus(HIV), the
Causative agent of AIDS,” Mathematical Medicine and Biology: A Journal of the IMA, vol. 3, no. 4, pp. 229-263, 1986.
[CrossRef] [Google Scholar] [Publisher Link]
[11] R.M. Anderson, “The Role of Mathematical Models in the Study of HIV Transmission and the Epidemiology of AIDS,” Journal
of Acquired Immune Deficiency Syndromes, vol. 1, no. 3, pp. 241-256, 1988.
[Google Scholar] [Publisher Link]
[12] H. de Arazoza, and R. Lounes, “A Nonlinear Model for Sexually Transmitted Diseases with Contact Tracing,” Mathematical
Medicine and Biology: A Journal of the IMA, vol. 19, no. 3, pp. 221–234, 2002.
[CrossRef] [Google Scholar] [Publisher Link]
[13] Brandy Rapatski et al., “Mathematical Epidemiology of HIV/AIDS in Cuba during the Period 1986-2000,” Mathematical
Biosciences and Engineering, vol. 3, no. 3, pp. 545-556, 2006.
[CrossRef] [Google Scholar] [Publisher Link]
[14] O. Diekmann, J.A.P. Heesterbeek, and J.A.J. Metz, “On the Definition and the Computation of the Basic Reproduction Ratio R0
in Models for Infectious Diseases in Heterogeneous Populations,” Journal of Mathematical Biology, vol. 28, no. 4, pp. 365-382,
1990.
[CrossRef] [Google Scholar] [Publisher Link]
[15] P. van den Driessche, and James Watmough, “Reproduction Numbers and sub-threshold Epidemic Equilibria for Compartmental
Models of Disease Transmission,” Mathematical Biosciences, vol. 180, no. 1-2, pp. 29-48, 2002.
[CrossRef] [Google Scholar] [Publisher Link]
[16] Stavros Busenberg, Kenneth Cooke, and Ying-Hen Hsieh, “A Model for HIV in Asia,” Mathematical Biosciences, vol. 128, no. 1-2,
pp. 185-210, 1995. [CrossRef] [Google Scholar] [Publisher Link]
[17] Klaus Dietz, “On the Transmission Dynamics of HIV,” Mathematical Biosciences, vol. 90, no. 1-2, pp. 397-414, 1988.
[CrossRef] [Google Scholar] [Publisher Link]
[18] Ying-Hen Hsieh, and Chien Hsun Chen, “Modeling the Social Dynamics of a Sex Industry: Its Implications for the Spread of
HIV/AIDS,” Bulletin of Mathematical Biology, vol. 66, pp. 143-166, 2004.
[CrossRef] [Google Scholar] [Publisher Link]
[19] Issa Shabani, Estomih S. Massawe, and Oluwole Daniel Makinde, “Modelling the Effect of Screening on the Spread of HIV
Infection in a Homogeneous Population with Infective Immigrants,” Scientific Researchs and Essays(SRE), vol. 6, no. 20, pp.
4397–4405, 2011.
[CrossRef] [Google Scholar] [Publisher Link]
[20] Jack H. Hale, Theory of Functional Differential Equations, 2nd ed., Springer Verlag, New York, 1977.
[CrossRef] [Publisher Link]
[21] Ali Raza et al., “Modeling the Effect of Delay Strategy on Transmission Dynamics of HIV/AIDS Disease, Advances in Difference
Equations, vol. 2020, no. 663, pp. 1-13, 2020.
[CrossRef] [Google Scholar] [Publisher Link]
[22] Sudip Samanta, “Effects of Awareness Program and Delay in the Epidemic Outbreak,” Mathematical Methods in the Applied
Sciences, vol. 40, no. 5, pp. 1679-1695, 2016.
[CrossRef] [Google Scholar] [Publisher Link]
Debashis Biswas, "Effect of Treatment and Awareness on HIV/AIDS Epidemic Model," International Journal of Mathematics Trends and Technology (IJMTT), vol. 70, no. 1, pp. 40-48, 2024. Crossref, https://doi.org/10.14445/22315373/IJMTT-V70I1P105